Ulcerative Colitis Treatment

Get the Most from Your Medication

Being on a maintenance medication involves "maintaining" consistency and following the dosing schedule your doctor prescribes.

Taking medication to treat or control a chronic condition like ulcerative colitis can lead to a real Catch-22: The better you feel, the more tempted you might be to cut back the dose or stop taking the medication. Yes, taking multiple pills, multiple times a day, may be an inconvenience. But when you start self-adjusting your dosage or forget to take your UC medication, you may not get the full benefit of your medical therapy and you may be at increased risk for a flare-up.

Remember that even if you're comfortable and able to perform normal activities, and you are not experiencing what you would call a flare, it doesn't mean all inflammation in your colon has subsided – or that inflamed tissue has healed completely. Maintenance medications can play an important role in treatment, even after your body feels "more or less normal" again.

Your doctor knows what's best when it comes to treatment and may change your medication or dosage over time to help maintain remission. Remember that ulcerative colitis is a lifelong condition with no cure except surgery. Maintenance therapy can help keep the condition under control.

Reward Yourself

Set a reasonable goal that you will take your medication as prescribed. Celebrate your success with loved ones or friends. After that, you can set a new milestone, and commit yourself to it. Then you can celebrate again.


Asacol (mesalamine) delayed-release tablets, available only by prescription, are indicated to treat mild to moderate flare-ups of ulcerative colitis and maintain remission of ulcerative colitis. Asacol is generally well tolerated. In studies of flare-ups, some people taking Asacol reported headache, abdominal pain, general pain, rash, upset stomach, and worsening of colitis symptoms. In a six month maintenance study, some people reported headache, runny nose, general pain, sore throat, infection, and nervousness. You should not take Asacol if you are allergic to Asacol or to salicylates such as aspirin. Tell your doctor if you have kidney problems or a history of kidney disease. It is recommended that all people have their kidney function tested prior to starting Asacol tablets and periodically while on Asacol therapy. Serious side effects may occur. If you have questions about taking Asacol, please talk to your doctor.
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