Understand Ulcerative Colitis

What is Ulcerative Colitis?

Ulcerative colitis involves inflammation of the inner lining of the colon and rectum. It's characterized by flare-ups followed by periods of remission that can alternate throughout a lifetime.

Flare-Ups

A flare-up is when the rectum and/or colon become inflamed. During a flare-up, people experience periods of increased symptoms of ulcerative colitis, such as diarrhea, rectal bleeding, abdominal pain or cramping, and an urgent need to go to the bathroom. Flare-ups can vary in duration and intensity.

Remission

Remission is the time between flare-ups of ulcerative colitis when people experience few, mild, or no ulcerative colitis symptoms. Periods of remission vary in duration, anywhere from a matter of days to a number of years.

While ulcerative colitis is a lifelong condition, flare-ups can be controlled and periods of remission extended with medication when taken as prescribed by your doctor. This condition affects people of all ages, but often is diagnosed during early adulthood. The causes of ulcerative colitis are unknown, but may involve heredity, infection, or the immune system. There is no known cure for ulcerative colitis except for removal of the colon. However, research organizations, such as the Crohn's & Colitis Foundation of America (CCFA), continue to research the cause of and seek a cure for Crohn's disease and ulcerative colitis.


Asacol (mesalamine) delayed-release tablets, available only by prescription, are indicated to treat mild to moderate flare-ups of ulcerative colitis and maintain remission of ulcerative colitis. Asacol is generally well tolerated. In studies of flare-ups, some people taking Asacol reported headache, abdominal pain, general pain, rash, upset stomach, and worsening of colitis symptoms. In a six month maintenance study, some people reported headache, runny nose, general pain, sore throat, infection, and nervousness. You should not take Asacol if you are allergic to Asacol or to salicylates such as aspirin. Tell your doctor if you have kidney problems or a history of kidney disease. It is recommended that all people have their kidney function tested prior to starting Asacol tablets and periodically while on Asacol therapy. Serious side effects may occur. If you have questions about taking Asacol, please talk to your doctor.
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